Acurable - Transforming Medical Diagnostics (with At-Home Wearables)

[Nicolas Chea]

Acurable - Transforming Medical Diagnostics (with At-Home Wearables)

May 7, 2025

Discover how Acurable, founded by Professor Esther Rodriguez-Villegas, is revolutionizing medical diagnostics with their user-friendly wearable medical devices designed for at-home use. Learn how their pioneering technology accelerates diagnosis and frees up clinician time, improving patient outcomes and healthcare efficiency. Explore the benefits of Acurable’s approach, including validated diagnostics, patient-friendly design, and seamless integration with healthcare workflows. Join the healthcare revolution with Acurable and enhance patient care with innovative diagnostic solutions.

Innovative Wearable Diagnostics:
Acurable develops wearable medical devices that empower patients to perform diagnostic tests at home, significantly reducing clinician workload. Named 'one to watch' on The Sunday Times Tech 100 list, Acurable is at the forefront of healthcare innovation.

The AcuPebble SA100:
The AcuPebble is Acurable’s first device, stemming from over a decade of research at Imperial College London. The device enables remote sleep apnoea diagnosis, endorsed by NICE in December, allowing NHS patients to undergo testing at home. AcuPebble, invented by Professor Esther Rodriguez-Villegas, is recommended for fully remote diagnosis, marking a major milestone in sleep health management.

Clinical Validation:
The AcuPebble SA100’s automated sleep apnoea diagnosis was validated at the NHS Royal Free London hospital. It demonstrated diagnostic equivalence to the gold-standard ambulatory method (multi-channel polygraphy with manual interpretation), achieving 94% PPV and 98% NPV.

Patient-Friendly Design:
AcuPebble prioritizes patient comfort and ease of use. The device is as simple as peeling off an adhesive and placing it on the neck. It requires no training and allows patients to sleep naturally at home without clinic visits.

How It Works:
The AcuPebble SA100 sensor is applied to the base of the neck, recording respiratory and cardiac sounds. Data is wirelessly transmitted to a mobile device and uploaded to a secure cloud platform. Signal processing algorithms analyze the data, producing a comprehensive diagnostic report within minutes, accessible through a user-friendly web interface.

Detailed Diagnostic Reporting:
AcuPebble generates a detailed sleep report that includes the overall diagnosis, AHI (flow reductions and desaturation), ODI (using both 3% and 4% desaturation criteria), and classification of apnoea events. The comprehensive analysis aids healthcare professionals in making accurate diagnoses efficiently.

Clinical Validation at the NHS Royal Free Hospital:
A powered clinical trial compared AcuPebble to the ambulatory gold-standard polygraphy, confirming diagnostic equivalence. All 150 patients successfully completed the test at home without training. Results were published in BMJ Open, showcasing the device’s usability and accuracy.

Revolutionizing Sleep Health:
Acurable’s commitment to innovation positions it as a leader in wearable diagnostics. With its clinically validated, patient-friendly devices, Acurable is set to transform how sleep apnoea is diagnosed and managed. By reducing the need for clinical visits and offering precise, automated diagnostics, Acurable enhances patient care and healthcare efficiency.

Contact Acurable
Website: https://acurable.com/en 

Reach out to Professor Esther Rodriguez-Villegas at -- https://www.linkedin.com/in/esther-rodriguez-villegas-5241bb4/?originalSubdomain=uk

to discuss partnerships or learn more about Acurable’s groundbreaking technology.

[James]

Brilliant write-up, Nicolas – really clear and engaging!

Acurable is exactly the kind of innovation we love seeing in the startup space. Making medical diagnostics more accessible and reducing pressure on the NHS is a huge win, and the clinical validation behind AcuPebble is seriously impressive. The fact that patients can get accurate sleep apnoea diagnoses from home, without training, speaks volumes about both the tech and the user-first design.

Great job spotlighting this founder and company. Looking forward to more features from you over the coming weeks!